Who are the companies leading the #celltherapy and #genetherapy clinical development space?

Download the below in .pdf here and get in touch (info@lqventures.com) for more info / last year’s view, or just read on…

Multiple companies have jumped in the Cell and / or Gene therapy space over the past couple of years. Advances in both the underlying tech (novel gene delivery and cell manipulation techniques etc.) as well as proof that cell and gene therapy assets can be approved and commercialized (IMLYGIC by BioVex, KYMRIAH by Novartis, LUXTURNA by Spark, YESCARTA by Kite Pharma and let’s not forget ZOLGENSMA by AveXis (Novartis) which is receiving negative publicity the last couple of days)

At LucidQuest (www.lqventures.com) we spend a significant amount of time conducting research in the Gene and Cell therapy space, focusing on better understanding the next key players and developments. Below you can find a quick update summary of the clinical trials (currently listed on clinicaltrials.gov) at Phase II+ and expected to read out this year or later. We have also included the companies behind those trials, an interesting mix of biotech and large pharma who have now embraced cell / gene therapy.

Below are the top companies who are active in the space currently. Iovance and Intra-Cellular Therapies stand out but also note GSKCelgenePfizerMSD (big pharma jumping into the space), Orchard and of course bluebird bio.

And here is a nice overview of all the companies (some of them also partnering with academic institutions and research centers) we have identified.

What about the top conditions / indications being investigated? See below….

What about the top conditions / indications being investigated? See below….

Hemophilia B, osteoarthritis and multiple neoplasms under investigation, with Duchenne Muscular Dystrophy, bipolar depression, NSCLC, Non-Hodgkin Lymphoma and even OC making an appearance…below you can also see the overview of all conditions / indications within our dataset.

…and that’s it! We will continue to track the space and discuss interesting developments as they take place. As mentioned earlier, you can download the above in .pdf here.

If you are a company or an investor who is interested or already active in the Cell and Gene Therapy space and you would like to get more insights and become / remain competitive in the space, drop us a message at info@lqventures.com or via www.lqventures.com and we will be in touch for an informal discussion.