Moderna’s mNexspike Approval, Breast Cancer Vaccine Progress, Malaria Trials in Kids & More 🌍💉🧠

In this week’s edition of Vaccine Research Updates, we spotlight the most critical advancements shaping the next era of immunization and disease prevention. From high-impact FDA approvals to breakthroughs in cancer, malaria, and pediatric vaccines—here’s what’s transforming global public health:

💉 Moderna’s next-gen COVID-19 vaccine, mNexspike, receives FDA approval for adults aged 65+ and high-risk individuals aged 12–64—offering higher antibody levels with a smaller dose.

🌿 Curevo initiates a Phase 2 shingles vaccine trial comparing amezosvatein to Shingrix in adults 50+—targeting safer, more accessible immunization.

🧬 Anixa completes a Phase 1 breast cancer vaccine trial—over 70 percent of participants show immune response, with Phase 2 trials planned alongside Cleveland Clinic.

🧠 Tedopi® by OSE Immunotherapeutics delivers 65 percent 1-year survival in pancreatic cancer—plus two complete responses and strong safety data.

🦟 Sanaria’s PfSPZ-LARC2 malaria vaccine expands to children aged 6–19 in Burkina Faso—aiming to reshape malaria prevention in Sub-Saharan Africa.

🧑‍⚕️ Canid secures $10M to scale its AI-powered pediatric vaccine management platform—reducing administrative burdens across 12 U.S. states.

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