Lung & Respiratory Breakthroughs: IPF Therapies, Asthma Innovations, COPD Advancements & More 🫁💊
This week’s Lung & Respiratory Health Updates brings you 10 cutting-edge developments shaping the future of pulmonary care. From game-changing IPF therapies and asthma rescue redefinitions to COPD breakthroughs, here’s everything you need to stay ahead in this rapidly evolving space:
💊 ArkBio’s AK3280 boosts FVC by over 209 mL in IPF, without the GI side effects of existing antifibrotics—Phase 3 is on the horizon.
🌿 PureTech’s deupirfenidone slows IPF progression by 80.9 percent vs placebo and maintains efficacy for a full year.
🧬 Endeavor’s ENV-101 increases lung volume by 142.3 mL and is the first to reduce pulmonary vessel volume in IPF.
🧪 Boehringer’s nerandomilast hits all endpoints in IPF and PPF with better tolerability—global NDA filings underway.
🫁 AstraZeneca’s Airsupra reduces severe asthma exacerbations by 47 percent and steroid use by 63 percent.
🔬 Connect Biopharma’s rademikibart improves lung function within 24 hours—stronger binding than dupilumab, without eosinophilia spikes.
🧱 Recludix’s STAT6 inhibitor rivals biologics for asthma without the toxicity risks of JAK inhibitors.
🌬️ Nuance Pharma’s ensifentrine shines in Phase 3 COPD trial with FEV1 gains up to 174 mL and 28 percent fewer exacerbations.
🔎 ReAlta’s RLS-0071 reduces airway inflammation markers in AE-COPD—mechanism confirmed via ChipCytometry.
🧠 Insmed’s brensocatib proves consistent in bronchiectasis subgroups—delivers QoL and lung function stability across diverse patients.
📢 Stay Ahead in Lung and Respiratory Health Research!
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