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Respiratory Weekly News – August 29th 2025

Respiratory

Respiratory

This Week in Respiratory Health: Breakthroughs in IPF, CF, COPD, MDR-TB, and More

From stem cell therapies for COPD to AI-powered diagnostics and major regulatory milestones, this week’s Respiratory Health Updates brings you the most critical developments transforming pulmonary care.

🧪 Key highlights:

🌬️ Savara’s molgramostim delivers statistically significant lung function improvements in aPAP—set for publication in NEJM

🧬 SMSbiotech kicks off the first-ever nebulized stem cell trial for COPD in Australia

💊 PureTech spins out Celea as deupirfenidone enters Phase 3 for IPF, outperforming pirfenidone by preserving lung function 50 percent better

🧩 Sionna starts first clinical trial targeting NBD1 stabilization in cystic fibrosis

🌿 Calluna’s CAL101 enters Phase 2 for IPF, targeting both inflammation and fibrosis

🛡️ BioVersys gains EMA orphan drug designation for its MDR-TB combination therapy with 10-year EU market exclusivity

🚀 Cereno’s CS1 wins FDA Fast Track status for PAH with promising vascular remodeling potential

🤝 MannKind expands its Technosphere®-based collaboration with United Therapeutics

🤖 Diag-Nose.io and Human Health secure $3M to develop AI-driven RhinoMAP for asthma and COPD optimization

🚨 Whether you’re tracking clinical innovation, regulatory progress, or digital health trends in pulmonary medicine, this roundup is your go-to source.

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