This Week in Respiratory Health: Global Respiratory Initiatives, CRISPR AMR Advances, Cystic Fibrosis Therapy & More

This week’s Respiratory Health Updates brings you pivotal breakthroughs—from global collaborations and FDA filings to cutting-edge CRISPR therapies and advances in cystic fibrosis treatment. Whether you’re working in biotech strategy, pulmonary R&D, or digital health innovation, these updates are essential for staying ahead in respiratory care.

🧪 Key highlights:

💊 Sanofi strengthens respiratory disease prevention initiatives in the UAE through a partnership with MoHAP to combat COPD, asthma, and tobacco use with early detection, risk reduction, and research collaborations.

🧬 Pliant Therapeutics halts bexotegrast development for idiopathic pulmonary fibrosis (IPF) after safety concerns from the BEACON-IPF trial.

🚀 SNIPR Biome raises €35 million to advance CRISPR-based therapies targeting antimicrobial resistance in cystic fibrosis patients, with plans to expand its pipeline.

🌫️ NHS approves once-daily triple therapy for cystic fibrosis—Alyftrek® shown to be as effective as Kaftrio®, with better patient compliance and quality of life improvements.

💉 Nuformix files FDA orphan drug application for NXP002, an inhaled tranilast therapy aimed at treating IPF.

🧫 Penn Medicine develops safer RNA therapies to reduce inflammation in RNA-based treatments, with potential applications in ARDS, heart attack, and stroke.

📱 Fosun Pharma licenses DPP-1 inhibitor XH-S004 globally—Expedition Therapeutics will manage its development for COPD and bronchiectasis, with the deal worth up to $645 million in milestones.

📉 INOVIO’s INO-3107 shows long-term reduction in RRP surgeries—A study reveals a significant drop in surgeries, with the overall response rate improving to 86%.

📈 Insmed reports Q2 results with growth in ARIKAYCE sales and Brensocatib FDA review—The company reports a 19% year-over-year increase, reaching $107.4 million in sales.

📢 Stay Ahead in Respiratory and Pulmonary Health Research!

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