Obesity Advancements: Arrowhead’s RNAi Debut, Lilly’s $870M Bet, Novo’s Triple Exit & More

In this week’s Obesity Updates, we spotlight the latest breakthroughs and big pharma maneuvers reshaping the obesity treatment landscape—from next-gen RNAi approaches to long-acting GLP-1 deals and industry-wide narrative shifts.

Key updates include:

🧬 Arrowhead launches Phase 1/2a trial for ARO-ALK7 targeting fat metabolism via RNAi

💉 Metsera’s amylin analog delivers 8.4% placebo-adjusted weight loss in early trials

❌ Novo Nordisk halts development of its triple-hormone obesity drug over safety concerns

🔬 BioAge doubles down on APJ agonists that mimic exercise and boost muscle function

💰 Lilly inks $870M partnership with Camurus for monthly GLP-1-based therapies

🗣️ Novo Nordisk and OAC launch campaign reframing obesity as a chronic disease

Explore how leading innovators are rewriting the rules of obesity care through novel mechanisms, strategic alliances, and patient-centered advocacy.

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