🧠 This Week in Neuroscience: FDA Breakthroughs, CAR-T Advancements, Gene Therapies, Brain Mapping and More
Get ready to explore the latest innovations in neuroscience! This week’s headlines feature game-changing updates in glioblastoma treatment, non-opioid pain therapies, brain atlas development, and next-gen gene therapy approaches. From FDA designations to AI-powered safety platforms, this roundup is packed with transformative progress in CNS science.
📌 What’s Inside This Week’s Update
💡 Quiver Bioscience secures $2.15M in NIH funding for an AI-powered CNS safety platform aimed at safer ASO development and reduced animal testing
🌍 JCR Pharmaceuticals reaches full Phase III trial enrollment for JR-141, a BBB-penetrating ERT already approved in Japan as IZCARGO for Hunter syndrome
📘 ASPN releases guidelines for 60-day SPRINT PNS therapy — a non-opioid, non-permanent option for chronic pain in back, knee, shoulder, and post-op settings
🎯 Mustang Bio earns FDA Orphan Drug Designation for MB-101 CAR-T therapy in GBM and astrocytomas, reporting a fifty percent disease control rate in Phase I
💥 Lexeo Therapeutics receives FDA Breakthrough Therapy Status for LX2006, a gene therapy for Friedreich Ataxia cardiomyopathy, with encouraging cardiac and neurologic data
🧬 Myosin Therapeutics validates NMII as a target in both addiction and glioblastoma; MT-125 extends survival in GBM models, while MT-110 enters clinical trials for stimulant use disorder
🧪 Dr. Xuyu Qian maps 18 million brain cells to create a spatial transcriptomic atlas of the human cortex, offering fresh insights into autism and cortical malformations
From precision CAR-T strategies to pioneering brain-mapping techniques, these developments are setting the stage for the next era in neuroscience.
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