🔬🩸 Hematology Updates: CAR-T Approvals, Mutation-Agnostic AML Therapies & Global Trial Milestones
🚀 New CAR-T approvals, breakthrough mutation-agnostic AML therapies, and paradigm-shifting clinical trial results are redefining the hematology landscape in 2025.
💡 Key Highlights This Week:
💥 UK approves Autolus’ Aucatzyl CAR-T for r/r ALL with 81% 12-month survival
🧪 Actimab-A shows efficacy across FLT3, TP53, KMT2A, and NPM1 AML mutations
🚀 Ingenium’s Gengleucel NK-cell therapy enters Phase 2 in MRD+ AML
🇪🇺 CHMP backs Calquence + Venetoclax combo for frontline CLL with up to 58% lower progression risk
🧫 Genmab to file sBLA for epcoritamab + R2 combo in relapsed FL
🧠 Genocury’s in vivo CAR-T achieves full remission in DLBCL without lymphodepletion
⚡ BioInvent’s BI-1808 earns FDA Fast Track for mycosis fungoides and Sézary syndrome
✅ EU approves Regeneron’s Lynozyfic for triple-class exposed multiple myeloma with 71% ORR
🎯 Whether you’re following CAR-T innovation, targeted radiotherapies, or trial design breakthroughs in blood cancers—this roundup delivers the insights you need to stay informed.
📢 Stay Ahead in Hematology Research!
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