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Endocrinology Weekly Update – September 2nd 2025

Endocrinology

Endocrinology

🧬 Endocrinology Update: Denosumab Approved, New Thyroid Guidelines, AI in Diabetes Care and More

From AI breakthroughs and next-gen diabetes therapies to regulatory shifts and biotech trials, this week’s update highlights the most impactful developments transforming how we understand, prevent, and treat endocrine disorders. Whether you’re a clinician, researcher, or health tech enthusiast—this is your weekly dose of what’s next.

📌 In This Episode:

💉 Abbott secures approval for the first denosumab biosimilar in Thailand, aiming to improve access to osteoporosis and cancer-related bone loss treatment.

🦠 New data confirms active surveillance is safe for patients with low-risk thyroid cancer—offering a long-term alternative to surgery.

📘 The American Thyroid Association (ATA) releases updated guidelines, raising the bar for thyroid cancer diagnosis, treatment, and survivorship care.

💊 The UK approves Oczyesa®, a once-monthly octreotide injection for acromegaly, enabling self-administration and improving patient convenience.

🥗 A Mediterranean diet and exercise slash type 2 diabetes risk by 31% over six years—compelling evidence supporting lifestyle intervention.

🧬 Groundbreaking research links DENND1A gene variants to testosterone overproduction in PCOS. CRISPR confirms the gene-to-hormone connection.

🧠 SGLT2 inhibitors are associated with a 20% lower risk of dementia in older adults—suggesting neuroprotective benefits beyond glucose control.

🌍 In China, Lilly and JD Health team up to expand digital access to diabetes and obesity medications, aiming to reach over 148 million diabetics and 500 million overweight adults.

💊 The FDA approves the first generic GLP-1 receptor agonist for weight loss—Teva’s liraglutide expands access to this fast-growing drug class.

🤖 AI meets maternal health: A smartphone-based photo scanner, powered by GPT-4 Vision, now helps patients manage gestational diabetes with real-time meal analysis and dietary guidance.

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