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AAAAI 2025 Preview: Key Allergy, Asthma and Immunology Highlights to Watch

AAAAI 2025 at a glance

As AAAAI 2025 approaches, LucidQuest highlights the key developments in allergy, asthma, immunology, and AI/ML to help you focus on the most relevant sessions.

📅 Build your schedule around the topics that interest you.

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Key Topics From AAAAI 2025 Scientific Presentations

Asthma & Respiratory Diseases

  • Dupilumab cuts exacerbations by 93% (RAPID).

  • Eos (≥150–500/µL) + FeNO (≥20) predict remission (QUEST).

  • EU-ADVANTAGE sees +16.5% lung function vs. other biologics. 🏹💨

Systemic Mastocytosis

  • Avapritinib, bezuclastinib, elenestinib thrive in ISM.

  • SUMMIT: bezuclastinib lowers tryptase (–94.4%) & mast cells (–92.3%), with 49.1% symptom gain.

  • JAK2 blockers may boost KIT inhibitor potency. 🏥🔬

Urticaria & Angioedema

  • Sebetralstat, navenibart redefine HAE.

  • Donidalorsen + garadacimab cut attacks 97%.

  • Remibrutinib + barzolvolimab sustain chronic urticaria control. 🦠💡

CRSwNP & Sinusitis

  • Depemokimab (2x/yr) lowers polyp scores.

  • Tezepelumab reduces surgery/steroids.

  • Dupilumab significantly boosts QoL in CRSwNP + AERD. 🌱⚕️

Food Allergy & Immunotherapy

  • Omalizumab beats OIT (36% vs. 19%) in multi-food allergy.

  • High-dose early peanut OIT fosters lasting tolerance (improved IgG4:IgE). 🍞💉

Atopic Dermatitis & Dermatology

  • IRL201104 is dose-responsive; tapinarof + ruxolitinib show broad efficacy.

  • Dupilumab normalizes amino acids, cuts pediatric AD inflammation. 🧴🩺

Pediatric Allergy

  • #Obesity raises allergic rhinitis risk (24%).

  • Stepwise egg OIT safe; VIASKIN peanut yields 73.3% response at 60 months (93% compliance). 🎈🌟

Immunology & Infection

  • Helminth coinfection may lessen severe COVID-19.

  • Dupilumab helps EoE regardless of diet.

  • Patch testing detects contact allergens in chronic ulcer care. 🌐🔬

Artificial Intelligence and Machine Learning at AAAAI 2025

AI in Environmental Health

  • Models fuse pollution/climate data to predict respiratory disease. 🤖📊

AI in Allergy & Asthma

  • ML refines allergen exposure, thunderstorm asthma, OIT education, and pollen tracking (94.7% accuracy). ⛅🌱

AI for Early Detection

  • EHR-based AI improves SM screening, oral food challenge forecasts, and tailored AR predictions. ⚙️🗂️

AI in Practice

  • Chatbots + predictive tools assist anaphylaxis response; performance gaps remain. 🚑🩺

AI for Equity & Fairness

  • Race-neutral AI lowers disparity in asthma hospitalizations, boosting care for underserved groups. 🤝⚖️

📅 Build your schedule around the topics that interest you.

📥 Download the AAAAI 2025_Preview_by_LucidQuest

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